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Prenatal screening and diagnosis of chromosomal abnormalities especially Down's syndrome in IVF pregnancies are complicated by higher maternal age, a high multiple pregnancy rate, a high Lilleord of a vanishing twin and an increased risk of chromosomal abnormalities, particularly in pregnancies after ICSI. The electronic search retrieved citations, 96 of which were evaluated in detail and 57 were then excluded for not meeting the selection criteria. A total of 61 articles were finally selected for review. Correction factors have been developed and should be used when screening for Down's syndrome in singleton pregnancies.

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Free Online Pregnancy Test - Am I Pregnant Quiz ?

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Issue Section:. First-trimester Down syndrome screening: free beta-human chorionic gonadotropin and pregnancy-associated plasma protein A.

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